' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 2 Researches
7.5
USERS' SCORE
Medium or Average
Based on 4 Reviews
6.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
667 mcg DFE (400 mcg Folic Acid)
167%
Calcium (as Calcium Carbonate)
100 mg
8%
Top Medical Research Studies
8
Folic acid improves angina symptoms
Study directly assesses folic acid
We explored the impact of folic acid on patients experiencing unstable angina and high levels of homocysteine, a condition associated with heart issues. Our investigation involved 52 individuals with unstable angina and 30 control subjects, measuring levels of plasma homocysteine, folic acid, and vitamin B12.
Patients identified with high homocysteine levels received 5 mg of folic acid for two months. We checked their homocysteine, folic acid, and vitamin B12 levels again after four and eight weeks. Additionally, we assessed how folic acid treatment affected the functioning of their arteries by measuring blood flow in the arms.
Our findings revealed that folic acid can successfully lower homocysteine levels and improve the functioning of arteries in those suffering from unstable angina. This suggests that folic acid may have a beneficial role in managing symptoms related to chest pain in these patients.
Patients identified with high homocysteine levels received 5 mg of folic acid for two months. We checked their homocysteine, folic acid, and vitamin B12 levels again after four and eight weeks. Additionally, we assessed how folic acid treatment affected the functioning of their arteries by measuring blood flow in the arms.
Our findings revealed that folic acid can successfully lower homocysteine levels and improve the functioning of arteries in those suffering from unstable angina. This suggests that folic acid may have a beneficial role in managing symptoms related to chest pain in these patients.
Read More
7
Folate's mixed effects on angina
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in a patient with coronary artery disease and repetitive miscarriages.
Lower relevance due to complexity
We explored the effects of folate treatment on a woman diagnosed with stable angina and a history of miscarriages, driven by hyperhomocysteinemia linked to the MTHFR C677T polymorphism. Her condition raised questions about whether supplementing with folic acid, along with vitamins B6 and B12, could alleviate her chest pain and improve her overall health.
Upon starting this combined treatment, we observed a notable 28.6% decrease in her homocysteine levels within two months. While this might suggest a positive trend towards her cardiovascular health, it's essential to highlight that despite the initial improvements, evidence regarding the long-term benefits of folate supplementation specifically for reducing chest pain has yet to be established.
Thus, while the vitamins showed effectiveness in lowering homocysteine levels, their role in significantly preventing future cardiovascular events remains uncertain. We acknowledge that further research will be necessary to better understand the broader implications of folate and its potential impact on conditions like angina and the associated risks.
Upon starting this combined treatment, we observed a notable 28.6% decrease in her homocysteine levels within two months. While this might suggest a positive trend towards her cardiovascular health, it's essential to highlight that despite the initial improvements, evidence regarding the long-term benefits of folate supplementation specifically for reducing chest pain has yet to be established.
Thus, while the vitamins showed effectiveness in lowering homocysteine levels, their role in significantly preventing future cardiovascular events remains uncertain. We acknowledge that further research will be necessary to better understand the broader implications of folate and its potential impact on conditions like angina and the associated risks.
Read More
Most Useful Reviews
9.5
Pain relief noted
Excellent! It significantly helps with my back pain, especially when taken with the B12 from 21st Century. The quality and price are great. I understand that folic acid is important for reducing deficiencies in the brain and spine, particularly during the first month of pregnancy when risks are highest. Please give a like, blessings to you!🙏🌻
Read More
4.8
Stomach pain observed
I believe it is better to take folate instead, as this form causes stomach pain.
Read More
3.8
Stomach issues reported
My son drinks it well, but it causes stomach pain even after eating. This wasn’t the case with other folic preparations.
Read More
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Medical Researches
SCIENTIFIC SCORE
Most Likely Effective
Based on 2 Researches
7.5
8
Folic acid improves angina symptoms
Study directly assesses folic acid
We explored the impact of folic acid on patients experiencing unstable angina and high levels of homocysteine, a condition associated with heart issues. Our investigation involved 52 individuals with unstable angina and 30 control subjects, measuring levels of plasma homocysteine, folic acid, and vitamin B12.
Patients identified with high homocysteine levels received 5 mg of folic acid for two months. We checked their homocysteine, folic acid, and vitamin B12 levels again after four and eight weeks. Additionally, we assessed how folic acid treatment affected the functioning of their arteries by measuring blood flow in the arms.
Our findings revealed that folic acid can successfully lower homocysteine levels and improve the functioning of arteries in those suffering from unstable angina. This suggests that folic acid may have a beneficial role in managing symptoms related to chest pain in these patients.
Patients identified with high homocysteine levels received 5 mg of folic acid for two months. We checked their homocysteine, folic acid, and vitamin B12 levels again after four and eight weeks. Additionally, we assessed how folic acid treatment affected the functioning of their arteries by measuring blood flow in the arms.
Our findings revealed that folic acid can successfully lower homocysteine levels and improve the functioning of arteries in those suffering from unstable angina. This suggests that folic acid may have a beneficial role in managing symptoms related to chest pain in these patients.
Read More
7
Folate's mixed effects on angina
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in a patient with coronary artery disease and repetitive miscarriages.
Lower relevance due to complexity
We explored the effects of folate treatment on a woman diagnosed with stable angina and a history of miscarriages, driven by hyperhomocysteinemia linked to the MTHFR C677T polymorphism. Her condition raised questions about whether supplementing with folic acid, along with vitamins B6 and B12, could alleviate her chest pain and improve her overall health.
Upon starting this combined treatment, we observed a notable 28.6% decrease in her homocysteine levels within two months. While this might suggest a positive trend towards her cardiovascular health, it's essential to highlight that despite the initial improvements, evidence regarding the long-term benefits of folate supplementation specifically for reducing chest pain has yet to be established.
Thus, while the vitamins showed effectiveness in lowering homocysteine levels, their role in significantly preventing future cardiovascular events remains uncertain. We acknowledge that further research will be necessary to better understand the broader implications of folate and its potential impact on conditions like angina and the associated risks.
Upon starting this combined treatment, we observed a notable 28.6% decrease in her homocysteine levels within two months. While this might suggest a positive trend towards her cardiovascular health, it's essential to highlight that despite the initial improvements, evidence regarding the long-term benefits of folate supplementation specifically for reducing chest pain has yet to be established.
Thus, while the vitamins showed effectiveness in lowering homocysteine levels, their role in significantly preventing future cardiovascular events remains uncertain. We acknowledge that further research will be necessary to better understand the broader implications of folate and its potential impact on conditions like angina and the associated risks.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 4 Reviews
6.2
9.5
Pain relief noted
Excellent! It significantly helps with my back pain, especially when taken with the B12 from 21st Century. The quality and price are great. I understand that folic acid is important for reducing deficiencies in the brain and spine, particularly during the first month of pregnancy when risks are highest. Please give a like, blessings to you!🙏🌻
Read More
4.8
Stomach pain observed
I believe it is better to take folate instead, as this form causes stomach pain.
3.8
Stomach issues reported
My son drinks it well, but it causes stomach pain even after eating. This wasn’t the case with other folic preparations.
2.5
Ongoing discomfort
It’s average; however, it has caused stomach pain. I've no idea why, but overall, I am in good health internally. This needs follow-up and improvement.
